Buprenorphine is a long acting, semi-synthetic partial opioid agonist with a strong affinity for the same receptors in the brain that opioids attach to. Buprenorphine can reduce and cravings and eliminate the euphoric effect of opiates and opioids.
At low doses buprenorphine produces sufficient agonist effect to enable opioid-addicted individuals to discontinue the misuse of opioids without experiencing withdrawal symptoms. The agonist effects of buprenorphine increase with increasing doses of the drug until it reaches a plateau and no longer continues to increase with further increases in dosage. This is called the "ceiling effect."
Colorado Addiction Treatment Services prescribes medications including naltrexone, acamprosate, topiramate and gabapentin to treatment alcohol use disorder. Research has shown that these medications, coupled with cognitive behavioral therapy, can reduce consumptions and cravings and prolong abstinence.